Dissection of sets of genes that control the character of wnt5a-deficient mouse calvarial cells.

@article{Guo2008DissectionOS,
  title={Dissection of sets of genes that control the character of wnt5a-deficient mouse calvarial cells.},
  author={Juanli Guo and Jianping Jin and Lyndon F. Cooper},
  journal={Bone},
  year={2008},
  volume={43 5},
  pages={
          961-71
        }
}
Wnts (wingless and int-related proteins) are a family of secreted cysteine-rich glycoproteins, expressed in a variety of tissues in developing embryos, thought to be involved in cell fate specification and stem cell commitment. To identify the specific Wnts involved in osteoblastic differentiation of human mesenchymal stem cells (hMSCs), we performed degenerative RT-PCR cloning method to amplify Wnt-encoding cDNAs expressed during osteoblastic differentiation of hMSCs in vitro and during hMSC… CONTINUE READING
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