Dissection of minimal sequence requirements for rhoptry membrane targeting in the malaria parasite.

@article{Cabrera2012DissectionOM,
  title={Dissection of minimal sequence requirements for rhoptry membrane targeting in the malaria parasite.},
  author={Ana Cabrera and Susann Herrmann and Dominik Warszta and Joana Mendonca Santos and Arun T John Peter and Maya Kono and Sandra Debrouver and Thomas Jacobs and Tobias Spielmann and Christian Ungermann and Dominique Soldati-Favre and Tim Wolf Gilberger},
  journal={Traffic},
  year={2012},
  volume={13 10},
  pages={1335-50}
}
Rhoptries are specialized secretory organelles characteristic of single cell organisms belonging to the clade Apicomplexa. These organelles play a key role in the invasion process of host cells by accumulating and subsequently secreting an unknown number of proteins mediating host cell entry. Despite their essential role, little is known about their biogenesis, components and targeting determinants. Here, we report on a conserved apicomplexan protein termed Armadillo Repeats-Only (ARO) protein… CONTINUE READING
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