Dissection of double-stranded RNA binding protein B2 from betanodavirus.

  title={Dissection of double-stranded RNA binding protein B2 from betanodavirus.},
  author={Beau James Fenner and Winnie Goh and Jimmy Kwang},
  journal={Journal of virology},
  volume={81 11},
Betanodaviruses are small RNA viruses that infect teleost fish and pose a considerable threat to marine aquaculture production. These viruses possess a small protein, termed B2, which binds to and protects double-stranded RNA. This prevents cleavage of virus-derived double-stranded RNAs (dsRNAs) by Dicer and subsequent production of small interfering RNA (siRNA), which would otherwise induce an RNA-silencing response against the virus. In this work, we have performed charged-to-alanine scanning… CONTINUE READING

From This Paper

Topics from this paper.
17 Citations
0 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 17 extracted citations

Similar Papers

Loading similar papers…