Dissection of an inverted X(p21.3q27.1) chromosome associated with mental retardation.

@article{Leprtre2003DissectionOA,
  title={Dissection of an inverted X(p21.3q27.1) chromosome associated with mental retardation.},
  author={Fr{\'e}d{\'e}ric Lepr{\^e}tre and Valerie Deken Delannoy and Philippe Froguel and Francis Vasseur and Claire Montpellier},
  journal={Cytogenetic and genome research},
  year={2003},
  volume={101 2},
  pages={124-9}
}
In a 6 year old boy referred for mental retardation, fragile X syndrome was ruled out by cytogenetic and molecular analyses. Cytogenetic investigations revealed an inverted X chromosome (p21.3q27.1). A similar chromosomal rearrangement was detected in his mildly mentally retarded mother. Fluorescence in situ hybridization (FISH), using a panel of ordered… CONTINUE READING