Dissection of C. elegans behavioral genetics in 3-D environments

  title={Dissection of C. elegans behavioral genetics in 3-D environments},
  author={Namseop Kwon and Ara B. Hwang and Young-Jai You and Seung-Jae V. Lee and Jung Ho Je},
  booktitle={Scientific reports},
The nematode Caenorhabditis elegans is a widely used model for genetic dissection of animal behaviors. Despite extensive technical advances in imaging methods, it remains challenging to visualize and quantify C. elegans behaviors in three-dimensional (3-D) natural environments. Here we developed an innovative 3-D imaging method that enables quantification of C. elegans behavior in 3-D environments. Furthermore, for the first time, we characterized 3-D-specific behavioral phenotypes of mutant… CONTINUE READING
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