Dissecting the role of the serotonin system in neuropsychiatric disorders using knockout mice

@article{Gingrich2001DissectingTR,
  title={Dissecting the role of the serotonin system in neuropsychiatric disorders using knockout mice},
  author={Jay A Gingrich and Ren{\'e} Hen},
  journal={Psychopharmacology},
  year={2001},
  volume={155},
  pages={1-10}
}
Rationale: The serotonin system has an important role in the modulation of several processes relevant to psychiatry such as anxiety, affect, aggression, and drug abuse. This review summarizes the recent progress in elucidating the function of the serotonergic system using knockout mice. This review while not exhaustive, highlights recent findings of relevance to psychopharmacology. Objectives: To familiarize the reader with the technique and the findings from serotonergic knockout mice. Methods… CONTINUE READING
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