Dissecting the pathophysiologic role of endogenous lectins: glycan-binding proteins with cytokine-like activity?

Abstract

Several families of endogenous glycan-binding proteins have been implicated in a wide variety of immunological functions including first-line defence against pathogens, cell trafficking, and immune regulation. These include, among others, the C-type lectins (collectins, selectins, mannose receptor, and others), S-type lectins (galectins), I-type lectins… (More)

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