Dissecting neural circuits for multisensory integration and crossmodal processing

@article{Yau2015DissectingNC,
  title={Dissecting neural circuits for multisensory integration and crossmodal processing},
  author={Jeffrey M. Yau and Gregory C. DeAngelis and Dora E. Angelaki},
  journal={Philosophical Transactions of the Royal Society B: Biological Sciences},
  year={2015},
  volume={370}
}
  • J. Yau, G. DeAngelis, D. Angelaki
  • Published 19 September 2015
  • Psychology, Biology
  • Philosophical Transactions of the Royal Society B: Biological Sciences
We rely on rich and complex sensory information to perceive and understand our environment. Our multisensory experience of the world depends on the brain's remarkable ability to combine signals across sensory systems. Behavioural, neurophysiological and neuroimaging experiments have established principles of multisensory integration and candidate neural mechanisms. Here we review how targeted manipulation of neural activity using invasive and non-invasive neuromodulation techniques have… 
View on Royal Society
royalsocietypublishing.org
45 Citations
Highly Influential Citations
2
Background Citations
19

Figures from this paper

45 Citations

Citation Type

Citation Type

Where are multisensory signals combined for perceptual decision-making?
Understanding the brain by controlling neural activity
TLDR
Carefully controlled behavioural experiments have been combined with electrical devices, targeted genetically encoded tools and neurochemical approaches to manipulate information processing in the brain to deepen understanding of brain function.
Impairments in Multisensory Integration after Stroke
TLDR
The impact of brain damage on MSI in stroke patients using a well-established psychophysical paradigm is demonstrated using the redundant target paradigm, the first to demonstrate the impact of head injury on multisensory integration in individuals with brain damage.
Homeostatic brain network mechanisms facilitate perceptual binding of audio-visual speech
TLDR
This work reports an enhancement of segregated information processing in distributed brain regions, defined as the perceptual binding network, which was anti-correlated with other intrinsic brain networks, such as dorsal attention and default mode networks during cross-modal perception.
Synergistic balance of local segregation and global integration mechanisms in large-scale brain networks underlies perceptual experience
TLDR
It is demonstrated using fMRI recordings that subjective perceptual experience of multisensory speech stimuli—real and illusory—are represented in differential states of segregation–integration balance and the perceptual binding network that exhibited this observation was anticorrelated with other intrinsic functional brain networks.
Title : Where are multisensory signals combined for perceptual 2 decision-making ?
TLDR
Manipulations of neuronal activity are required to establish causal roles for given brain regions in multisensory perceptual decision-making, and so far indicate that distributed networks underlie mult isensory decision- making.
Cross-Talk of Low-Level Sensory and High-Level Cognitive Processing: Development, Mechanisms, and Relevance for Cross-Modal Abilities of the Brain
TLDR
The mechanisms underlying the integration of multiple senses and how cross-modal processing in primary sensory cortices might be modified by top-down modulation of the PFC are summarized and the critical factors and developmental mechanisms that account for the interaction between neuronal networks involved in sensory and cognitive processing are examined.
Playing the electric light orchestra—how electrical stimulation of visual cortex elucidates the neural basis of perception
  • Nela Cicmil, K. Krug
  • Biology
    Philosophical Transactions of the Royal Society B: Biological Sciences
  • 2015
TLDR
The function and organization of visual cortex is reconsidered according to results obtained from stimulation techniques, with a special emphasis on electrical stimulation of small groups of cells in awake subjects who can report their visual experience.
Two parallel pathways convey distinct visual information to the Drosophila mushroom body
TLDR
Two novel types of mushroom body input neuron that connect a processing center — the lobula— to the dorsal accessory calyx of the mushroom body are identified, which could be a fundamental feature of the neuronal architecture underlying multisensory integration in associative brain centers.
Associative learning changes cross-modal representations in the gustatory cortex
TLDR
The results show that the gustatory cortex represents cross- modal stimuli according to their sensory identity, and that learning changes the overlap of cross-modal representations.
...
...

References

SHOWING 1-10 OF 159 REFERENCES
Is neocortex essentially multisensory?
Crossmodal binding through neural coherence: implications for multisensory processing
Multisensory integration: psychophysics, neurophysiology, and computation
Multisensory Interplay Reveals Crossmodal Influences on ‘Sensory-Specific’ Brain Regions, Neural Responses, and Judgments
Development of multisensory integration from the perspective of the individual neuron
TLDR
This work has shown that neurons in a newborn's brain are not capable of multisensory integration, and studies in the midbrain have shown that the development of this process is not predetermined.
Multisensory spatial interactions: a window onto functional integration in the human brain
Multisensory Integration: Flexible Use of General Operations
Organization and plasticity in multisensory integration: early and late experience affects its governing principles.
Neuromodulation of Early Multisensory Interactions in the Visual Cortex
TLDR
It is shown that redundant multisensory stimuli can increase visual cortical excitability, as measured by means of phosphene induction by occipital TMS; such physiological enhancement is followed by a behavioral facilitation through the amplification of signal intensity in sensory-specific visual areas.
The multifaceted interplay between attention and multisensory integration
...
...