Dissecting functional impairment in hypertrophic cardiomyopathy by dynamic assessment of diastolic reserve and outflow obstruction: A combined cardiopulmonary-echocardiographic study.

@article{Re2017DissectingFI,
  title={Dissecting functional impairment in hypertrophic cardiomyopathy by dynamic assessment of diastolic reserve and outflow obstruction: A combined cardiopulmonary-echocardiographic study.},
  author={Federica Re and Elisabetta Zachara and Andrea Avella and Pasquale Baratta and Michele Di Mauro and Massimo Uguccioni and Iacopo Olivotto},
  journal={International journal of cardiology},
  year={2017},
  volume={227},
  pages={
          743-750
        }
}
BACKGROUND Exercise limitation in hypertrophic cardiomyopathy (HCM) patients is often attributed to left ventricular outflow tract (LVOT) obstruction and diastolic impairment. However, these features assessed at rest fail to predict performance. To evaluate their variations and interplay during effort in HCM, we performed echocardiographic assessment of diastolic function and outflow obstruction during cardiopulmonary test (CPX). METHODS We included 197 HCM patients (mean age 45±15years, 129… CONTINUE READING