Dissecting cancer through mathematics: from the cell to the animal model

  title={Dissecting cancer through mathematics: from the cell to the animal model},
  author={H. Byrne},
  journal={Nature Reviews Cancer},
  • H. Byrne
  • Published 2010
  • Medicine
  • Nature Reviews Cancer
  • This Timeline article charts progress in mathematical modelling of cancer over the past 50 years, highlighting the different theoretical approaches that have been used to dissect the disease and the insights that have arisen. Although most of this research was conducted with little involvement from experimentalists or clinicians, there are signs that the tide is turning and that increasing numbers of those involved in cancer research and mathematical modellers are recognizing that by working… CONTINUE READING
    294 Citations

    Figures and Topics from this paper.

    Explore Further: Topics Discussed in This Paper

    The mathematics of cancer: integrating quantitative models
    • 354
    • PDF
    Mathematical Models of Cancer Cell Plasticity
    Computational Modelling of Metastasis Development in Renal Cell Carcinoma
    • 30
    • PDF
    Mechanobiology of tumor invasion: engineering meets oncology.
    • 51


    A history of the study of solid tumour growth: The contribution of mathematical modelling
    • 617
    • PDF
    Modelling aspects of cancer dynamics: a review
    • 204
    Nonlinear modelling of cancer: bridging the gap between cells and tumours.
    • 407
    • PDF
    Towards whole-organ modelling of tumour growth.
    • 105
    • PDF
    In silico cancer modeling: is it ready for prime time?
    • 120
    Cancer Modelling and Simulation
    • 319
    Modeling Somatic Evolution in Tumorigenesis
    • 105
    • PDF
    A mathematical model of breast and ovarian cancer treated with paclitaxel.
    • 81