Dissecting Timing Variability in Yeast Meiosis

  title={Dissecting Timing Variability in Yeast Meiosis},
  author={Iftach Nachman and Aviv Regev and Sharad Ramanathan},
Cell-to-cell variability in the timing of cell-fate changes can be advantageous for a population of single-celled organisms growing in a fluctuating environment. We study timing variability during meiosis in Saccharomyces cerevisiae, initiated upon nutritional starvation. We use time-lapse fluorescence microscopy to measure the timing of meiotic events in single cells and find that the duration of meiosis is highly variable between cells. This variability is concentrated between the beginning… CONTINUE READING

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