Disruption of virus-host cell interactions and cell signaling pathways as an anti-viral approach against influenza virus infections.

@article{Ludwig2011DisruptionOV,
  title={Disruption of virus-host cell interactions and cell signaling pathways as an anti-viral approach against influenza virus infections.},
  author={Stephan Ludwig},
  journal={Biological chemistry},
  year={2011},
  volume={392 10},
  pages={837-47}
}
Influenza is still one of the major plagues worldwide with the threatening potential to cause pandemics. In recent years, increasing levels of resistance to the four FDA approved anti-influenza virus drugs have been described. This situation underlines the urgent need for novel anti-virals in preparation for future influenza epidemics or pandemics. Although the anti-virals currently in use target viral factors such as the neuraminidase or the M2 ion channel, there is an increase in pre-clinical… CONTINUE READING
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