Disruption of tubulobulbar complex by high intratesticular estrogens leading to failed spermiation.

@article{Dsouza2009DisruptionOT,
  title={Disruption of tubulobulbar complex by high intratesticular estrogens leading to failed spermiation.},
  author={R. D'souza and S. Pathak and R. Upadhyay and Reshma Gaonkar and S. D'Souza and S. Sonawane and M. Gill-Sharma and N. Balasinor},
  journal={Endocrinology},
  year={2009},
  volume={150 4},
  pages={
          1861-9
        }
}
Spermiation is the final phase of spermatogenesis leading to release of mature spermatids into the lumen of the seminiferous tubules. Morphologically, it involves a series of events, namely removal of excess spermatid cytoplasm, removal of ectoplasmic specialization, formation of tubulobulbar complex, and final disengagement of the spermatid from the Sertoli cell. Previous studies in our laboratory have shown that administration of 17beta-estradiol at a dose of 100 microg/kg body weight for 10… Expand
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