Disruption of tight junctions and induction of proinflammatory cytokine responses in colonic epithelial cells by Campylobacter jejuni.

@article{Chen2006DisruptionOT,
  title={Disruption of tight junctions and induction of proinflammatory cytokine responses in colonic epithelial cells by Campylobacter jejuni.},
  author={Ming Li Chen and Zhongming Ge and James G Fox and David B. Schauer},
  journal={Infection and immunity},
  year={2006},
  volume={74 12},
  pages={6581-9}
}
Campylobacter jejuni is a leading cause of human enterocolitis and is associated with postinfectious complications, including irritable bowel syndrome and Guillain-Barré syndrome. However, the pathogenesis of C. jejuni infection remains poorly understood. Paracellular pathways in intestinal epithelial cells are gated by intercellular junctions (tight junctions and adherens junctions), providing a functional barrier between luminal microbes and host immune cells in the lamina propria. Here we… CONTINUE READING
73 Citations
66 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 73 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 66 references

Similar Papers

Loading similar papers…