Disruption of the taurine transporter gene (taut) leads to retinal degeneration in mice.

@article{HellerStilb2002DisruptionOT,
  title={Disruption of the taurine transporter gene (taut) leads to retinal degeneration in mice.},
  author={Birgit Heller-Stilb and Claudia R C van Roeyen and Kristina Rascher and H. P. Hartwig and Andrea G Huth and Mathias Wolfgang Seeliger and Ulrich Warskulat and Dieter H{\"a}ussinger},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year={2002},
  volume={16 2},
  pages={231-3}
}
Taurine is involved in cell volume homeostasis, antioxidant defense, protein stabilization, and stress responses. High levels of intracellular taurine are maintained by a Na+-dependent taurine transporter (TAUT) in the plasma membrane. In view of the immunomodulatory and cytoprotective effects of taurine, a mouse model with a disrupted gene coding for the… CONTINUE READING