Disruption of the epithelial barrier during intestinal inflammation: Quest for new molecules and mechanisms.

Abstract

The intestinal epithelium forms a key protective barrier that separates internal organs from the harmful environment of the gut lumen. Increased permeability of the gut barrier is a common manifestation of different inflammatory disorders contributing to the severity of disease. Barrier permeability is controlled by epithelial adherens junctions and tight… (More)
DOI: 10.1016/j.bbamcr.2017.03.007

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