Disruption of the acetate kinase (ack) gene of Clostridium acetobutylicum results in delayed acetate production


In microorganisms, the enzyme acetate kinase (AK) catalyses the formation of ATP from ADP by de-phosphorylation of acetyl phosphate into acetic acid. A mutant strain of Clostridium acetobutylicum lacking acetate kinase activity is expected to have reduced acetate and acetone production compared to the wild type. In this work, a C. acetobutylicum mutant… (More)
DOI: 10.1007/s00253-011-3848-4


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