Disruption of the ErbB signaling in adolescence increases striatal dopamine levels and affects learning and hedonic-like behavior in the adult mouse.

Abstract

The ErbB signaling pathway has been genetically and functionally implicated in schizophrenia. Numerous findings support the dysregulation of Neuregulin (NRG) and epidermal growth factor (EGF) signaling in schizophrenia. However, it is unclear whether alterations of these pathways in the adult brain or during development are involved in the pathophysiology… (More)
DOI: 10.1016/j.euroneuro.2014.09.011

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Cite this paper

@article{Golani2014DisruptionOT, title={Disruption of the ErbB signaling in adolescence increases striatal dopamine levels and affects learning and hedonic-like behavior in the adult mouse.}, author={Idit Golani and Hagar Tadmor and Andr{\'e}s Buonanno and Ilana Kremer and Alon Shamir}, journal={European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology}, year={2014}, volume={24 11}, pages={1808-18} }