Disruption of self-organized actions in monkeys with progressive MPTP-induced parkinsonism. I. Effects of task complexity.

@article{Pessiglione2004DisruptionOS,
  title={Disruption of self-organized actions in monkeys with progressive MPTP-induced parkinsonism. I. Effects of task complexity.},
  author={Mathias Pessiglione and Dominique Guehl and Etienne C. Hirsch and Jean F{\'e}ger and L{\'e}on Tremblay},
  journal={The European journal of neuroscience},
  year={2004},
  volume={19 2},
  pages={426-36}
}
Parkinson's disease (PD) is characterized by motor symptoms, usually accompanied by cognitive deficits. The question addressed in this study is whether complexity of routine actions can exacerbate parkinsonian disorders that are often considered to be motor symptoms. To examine this question, we trained four vervet monkeys (Cercopithecus aethiops) to perform three multiple-choice retrieval tasks. In order of ascending complexity, rewards were freely available (task 1), covered with transparent… CONTINUE READING