Disruption of quercetin metabolism by fungicide affects energy production in honey bees (Apis mellifera).

@article{Mao2017DisruptionOQ,
  title={Disruption of quercetin metabolism by fungicide affects energy production in honey bees (Apis mellifera).},
  author={Wenfu Mao and Mary A. Schuler and May R Berenbaum},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2017},
  volume={114 10},
  pages={2538-2543}
}
Cytochrome P450 monooxygenases (P450) in the honey bee, Apis mellifera, detoxify phytochemicals in honey and pollen. The flavonol quercetin is found ubiquitously and abundantly in pollen and frequently at lower concentrations in honey. Worker jelly consumed during the first 3 d of larval development typically contains flavonols at very low levels, however. RNA-Seq analysis of gene expression in neonates reared for three days on diets with and without quercetin revealed that, in addition to up… CONTINUE READING