Disruption of microbial cells for intracellular products

  title={Disruption of microbial cells for intracellular products},
  author={Yusuf Chisti and Murray Moo-Young},
Disintegration of microbial cells is a necessary first step for the production of intracellular enzymes and organelIes. With increasing use o f intracellular microbial material in industry and medicine, the cell disruption unit operation is gaining in importance. This review examines the state of the art o f the largescale cell disruption technology and disruption methods o f potential commercial value. 
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