Disruption of learning by excitatory amino acid receptor antagonists.

  title={Disruption of learning by excitatory amino acid receptor antagonists.},
  author={S Baron and J. M. Moerschbaecher},
  journal={Behavioural pharmacology},
  volume={7 6},
Compounds that act as competitive or uncompetitive N-methyl-D-aspartate (NMDA) antagonists, glycine/NMDA-site antagonists, or alpha-amino-2,3-dihydro-5-methyl-3-oxo-4-isoxalzolepropionic acid (AMPA)-receptor antagonists were evaluated for effects on a repeated acquisition of behavioral chains schedule by rats. Responding by rats was maintained by food presentation under a repeated acquisition or a performance procedure. Under the repeated acquisition procedure, subjects acquired a different… CONTINUE READING
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