Disruption of conditioned reaction time performance by dopamine receptor antagonists in the rat.


The effects of the neuroleptics haloperidol, cis-flupenthixol and chlorpromazine, and the selective dopamine (DA) receptor antagonists raclopride and SCH 23390, were assessed in a conditioned reaction time task. In this operant task, rats were required to hold down a lever for a randomly determined hold duration (0.5-2.0s) and to release the lever within 1s… (More)