Disruption of circadian insulin secretion is associated with reduced glucose uptake in first-degree relatives of patients with type 2 diabetes.

@article{Boden1999DisruptionOC,
  title={Disruption of circadian insulin secretion is associated with reduced glucose uptake in first-degree relatives of patients with type 2 diabetes.},
  author={Guenther Boden and Xiaoli Chen and Marcia Polansky},
  journal={Diabetes},
  year={1999},
  volume={48 11},
  pages={2182-8}
}
The objective of this study was to evaluate whether first-degree relatives (FDRs) of patients with type 2 diabetes had abnormal circadian insulin secretion and, if so, whether this abnormality affected their glucose metabolism. Six African-American FDRs with normal glucose tolerance and 12 matched normal control subjects (who had no family history of… CONTINUE READING