Disruption of central nervous system barriers in multiple sclerosis.

@article{Alvarez2011DisruptionOC,
  title={Disruption of central nervous system barriers in multiple sclerosis.},
  author={Jorge Iv{\'a}n Calle Alvarez and Romain Cayrol and Alexandre Prat},
  journal={Biochimica et biophysica acta},
  year={2011},
  volume={1812 2},
  pages={
          252-64
        }
}
The delicate microenvironment of the central nervous system (CNS) is protected by the blood-brain barrier (BBB) and the blood-cerebrospinal fluid barrier (BCB). These barriers function in distinct CNS compartments and their anatomical basis lay on the junctional proteins present in endothelial cells for the BBB and in the choroidal epithelium for the BCB. During neuroinflammatory conditions like multiple sclerosis (MS) and its murine model experimental autoimmune encephalomyelitis (EAE… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 191 REFERENCES

The blood-brain barrier/neurovascular unit in health and disease.

  • Pharmacological reviews
  • 2005
VIEW 11 EXCERPTS
HIGHLY INFLUENTIAL

CD73 is required for efficient entry of lymphocytes into the central nervous system during experimental autoimmune encephalomyelitis.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2008
VIEW 10 EXCERPTS
HIGHLY INFLUENTIAL

IFN-beta regulates CD73 and adenosine expression at the blood-brain barrier.

  • European journal of immunology
  • 2008
VIEW 10 EXCERPTS
HIGHLY INFLUENTIAL

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