Disruption of a novel MFS transporter gene, DIRC2, by a familial renal cell carcinoma-associated t(2;3)(q35;q21).

Abstract

Previously, we described a family with a significantly increased predisposition for renal cell cancer co-segregating with a t(2;3)(q35;q21) chromosomal translocation. Several primary tumors of the clear cell type from different family members were analyzed at a molecular level. Loss of the derivative chromosome 3 was consistently found. In addition… (More)

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@article{Bodmer2002DisruptionOA, title={Disruption of a novel MFS transporter gene, DIRC2, by a familial renal cell carcinoma-associated t(2;3)(q35;q21).}, author={Dani{\"{e}lle Bodmer and Marc J. Eleveld and Ellen Kater-Baats and Irene C M Janssen and B. Janssen and Marian A. J. Weterman and Eric F. P. M. Schoenmakers and Michael L. Nickerson and Marston Linehan and B. Zbar and Ad Geurts van Kessel}, journal={Human molecular genetics}, year={2002}, volume={11 6}, pages={641-9} }