Disrupted reinforcement signaling in the orbitofrontal cortex and caudate in youths with conduct disorder or oppositional defiant disorder and a high level of psychopathic traits.

@article{Finger2011DisruptedRS,
  title={Disrupted reinforcement signaling in the orbitofrontal cortex and caudate in youths with conduct disorder or oppositional defiant disorder and a high level of psychopathic traits.},
  author={Elizabeth C. Finger and Abigail A. Marsh and Karina S. Blair and Marguerite E Reid and Courtney Sims and Pamela Ng and Daniel S. Pine and R. James R. Blair},
  journal={The American journal of psychiatry},
  year={2011},
  volume={168 2},
  pages={152-62}
}
OBJECTIVE Dysfunction in the amygdala and orbitofrontal cortex has been reported in youths and adults with psychopathic traits. The specific nature of the functional irregularities within these structures remains poorly understood. The authors used a passive avoidance task to examine the responsiveness of these systems to early stimulus-reinforcement exposure, when prediction errors are greatest and learning maximized, and to reward in youths with psychopathic traits and comparison youths… CONTINUE READING
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