Disproportionate Reduction of Serotonin Transporter May Predict the Response and Adherence to Antidepressants in Patients with Major Depressive Disorder: A Positron Emission Tomography Study with 4-[18F]-ADAM

@inproceedings{Yeh2015DisproportionateRO,
  title={Disproportionate Reduction of Serotonin Transporter May Predict the Response and Adherence to Antidepressants in Patients with Major Depressive Disorder: A Positron Emission Tomography Study with 4-[18F]-ADAM},
  author={Yi-Wei Yeh and Pei-Shen Ho and Shiue-mei Kuo and Chun-Yen Chen and Chih-Sung Liang and Che-Hung Yen and Chang-Chih Huang and Kuo-Hsing Ma and Chyng-Yann Shiue and Wen-Sheng Huang and Jia-Fwu Shyu and Fang-jung Wan and Ru-Band Lu and San-Yuan Huang},
  booktitle={The international journal of neuropsychopharmacology},
  year={2015}
}
BACKGROUND Many lines of evidence suggest the role of serotonin transporter (SERT)-mediated reuptake of serotonin in the pathophysiology and treatment of major depressive disorder (MDD). This study aimed to examine whether the pretreatment of SERT binding potential or SERT binding ratio between terminal projection regions relative to the midbrain raphe nuclei was associated with treatment outcomes to SERT-targeted antidepressants. METHODS We recruited 39 antidepressant-naïve patients with MDD… CONTINUE READING
Tweets
This paper has been referenced on Twitter 2 times. VIEW TWEETS

References

Publications referenced by this paper.
SHOWING 1-10 OF 83 REFERENCES

Regional differences in SERT occupancy after acute and prolonged SSRI intake investigated by brain PET

  • P Baldinger, GS Kranz, +9 authors S Kasper
  • Neuroimage
  • 2014
1 Excerpt

Regional differences in SERT occupancy after acute and prolonged SSRI intake investigated by brain PET. Neuroimage 88:252–262

  • P Baldinger, GS Kranz, +9 authors S Kasper
  • 2014
2 Excerpts

Similar Papers

Loading similar papers…