Disposition of cefotaxime in rat, dog and man.


The excretory pathway for the elimination of 14C-cefotaxime (14C-HR 756) was found to be the same for rat, dog and man with elimination into the urine being the most important route, accounting for greater than 80% of the dosed radioactivity. The amounts of unchanged cefotaxime eliminated in the urine ranged from 20-32% in rat and dog to 56% in man. The… (More)


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