Disposition of antineoplastic agents in the very young child.

  title={Disposition of antineoplastic agents in the very young child.},
  author={Ping Liao and Mary V. Relling and William R. Crom and K Silverstein and Steven Groom and John H. Rodman and Gaston K. Rivera and William M. Crist and William E. Evans},
  journal={The British journal of cancer. Supplement},
Maturation of physiologic process which govern the disposition of pharmacologic agents can yield significant changes in absorption, distribution, metabolism, and elimination of drugs in neonates, infants and children. However, there are very little data concerning the disposition of anticancer drugs in young children. Pharmacokinetic data for six anticancer agents were compared in infants less than 1 year of age and children greater than 1 year of age treated at St Jude Children's Research… CONTINUE READING
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