Disposition and elimination of three polychlorinated dibenzofurans in the liver of the rat.

Abstract

The disposition and elimination of 1,2,3,6,7,8-HxCDF (HxCDF), 1,2,3,7,8-PnCDF (1-PnCDF), and 2,3,4,7,8-PnCDF (4-PnCDF) were studied in liver of female Sprague-Dawley rats after administration of a single oral dose of 3.5-6.3 micrograms/kg. The disposition of these PCDF congeners was structure and vehicle dependent. Administration in peanut oil caused the… (More)

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