Disposition and dosage regimen of cephaloridine in calves

  title={Disposition and dosage regimen of cephaloridine in calves},
  author={Rakesh Kumar Chaudhary and A. K. Srivastava},
  journal={Veterinary Research Communications},
The disposition and dosage regimen of cephaloridine were investigated in healthy calves following a single intramuscular administration of 10 mg/kg. The absorption halflife, climination halflife, apparent volume of distribution and total body clearance were 0.107±0.025 h, 2.08±0.14 h, 0.70±0.07L kg-1 and 235.8±21.9 ml kg-1 h-1, respectively. Therapeutic plasma levels (≥1 μg/ml) were maintained for up to 7 h. A satisfactory intramuscular dosage regimen for cephaloridine in calves would be 10 mg… 


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