Disposition Kinetics, Urinary Excretion and Dosage Regimen of Levofloxacin Formulation Following Single Intravenous Administration in Crossbred Calves

@article{Dumka2007DispositionKU,
  title={Disposition Kinetics, Urinary Excretion and Dosage Regimen of Levofloxacin Formulation Following Single Intravenous Administration in Crossbred Calves},
  author={Vinod Kumar Dumka and Anil Kumar Srivastava},
  journal={Veterinary Research Communications},
  year={2007},
  volume={31},
  pages={873-879}
}
Levofloxacin ((−)-9-fluoro-3-methyl-10-(4-methyl-1-piprazinyl)-7-oxo-2,3-dihydro-7Hpyrido [1,2,3-de]-[1,4]-benzoxazine-6-carboxylic acid), a recently introduced second-generation fluoroquinolone, possesses excellent activity against Gram-positive, Gram-negative and anaerobic bacteria (Davis and Bryson, 1994; North et al., 1998). Compared to other fluoroquinolones, ofloxacin and ciprofloxacin, it also has more pronounced bactericidal activity against organisms such as Pseudomonas… CONTINUE READING
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