Disposable cartridge extraction of retinol and alpha-tocopherol from fatty samples.

@article{Bourgeois1988DisposableCE,
  title={Disposable cartridge extraction of retinol and alpha-tocopherol from fatty samples.},
  author={C F Bourgeois and N Ciba},
  journal={Journal - Association of Official Analytical Chemists},
  year={1988},
  volume={71 1},
  pages={12-5}
}
A new approach is proposed for liquid/solid extraction of retinol and alpha-tocopherol from samples, using a disposable kieselguhr cartridge. The substitution of the mixture methanol-ethanol-n-butanol (4 + 3 + 1) for methanol in the alkaline hydrolysis solution makes it now possible to process fatty samples. Methanol is necessary to solubilize the antioxidant ascorbic acid, and a linear chain alcohol such as n-butanol is necessary to reduce the size of soap micelles so that they can penetrate… CONTINUE READING