Displacement of cellular proteins by functional analogues from plasmids or viruses could explain puzzling phylogenies of many DNA informational proteins.

@article{Forterre1999DisplacementOC,
  title={Displacement of cellular proteins by functional analogues from plasmids or viruses could explain puzzling phylogenies of many DNA informational proteins.},
  author={Patrick Forterre},
  journal={Molecular microbiology},
  year={1999},
  volume={33 3},
  pages={457-65}
}
Comparative genomics has revealed many examples in which the same function is performed by unrelated or distantly related proteins in different cellular lineages. In some cases, this has been explained by the replacement of the original gene by a paralogue or non-homologue, a phenomenon known as non-orthologous gene displacement. Such gene displacement probably occurred early on in the history of proteins involved in DNA replication, repair, recombination and transcription (DNA informational… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 65 references

Archaea and the

  • D. R. Edgell, W. F. Doolittle
  • 1997
Highly Influential
6 Excerpts

New hypotheses about the origins of viruses , prokaryotes and eukaryotes

  • P. Forterre
  • Frontiers of Life
  • 1992
Highly Influential
4 Excerpts

1998b) You are what you eat: a gene transfer

  • W. F. Doolittle
  • Q 1999 Blackwell Science Ltd, Molecular…
  • 1999

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