Displacement correlations between a single mesenchymal-like cell and its nucleus effectively link subcellular activities and motility in cell migration analysis

@inproceedings{Lan2016DisplacementCB,
  title={Displacement correlations between a single mesenchymal-like cell and its nucleus effectively link subcellular activities and motility in cell migration analysis},
  author={Tian Lan and Kai Chien Cheng and Tina Ren and Stephen Hugo Arce and Yiider Tseng},
  booktitle={Scientific reports},
  year={2016}
}
Cell migration is an essential process in organism development and physiological maintenance. Although current methods permit accurate comparisons of the effects of molecular manipulations and drug applications on cell motility, effects of alterations in subcellular activities on motility cannot be fully elucidated from those methods. Here, we develop a strategy termed cell-nuclear (CN) correlation to parameterize represented dynamic subcellular activities and to quantify their contributions in… CONTINUE READING

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