Dispersion reduction in pressure-driven flow through microetched channels.

  title={Dispersion reduction in pressure-driven flow through microetched channels.},
  author={Debashis Dutta and David T Leighton},
  journal={Analytical chemistry},
  volume={73 3},
Fluid is often moved about microetched channels in lab-on-a-chip applications using electrokinetic flows (electrophoresis or electroosmosis) rather than pressure-driven flows because the latter result in large Taylor dispersion. However, small pressure gradients may arise unintentionally in such systems due to a mismatch in electroosmotic flow rates or hydrostatic pressure differentials along the microetched channel. Under laminar flow conditions, Doshi et al. (Chem. Eng. Sci. 1978, 33, 795-804… CONTINUE READING
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