Dispersion of 'refractoriness' in noninfarcted myocardium of patients with ventricular tachycardia or ventricular fibrillation after myocardial infarction.

@article{Misier1995DispersionO,
  title={Dispersion of 'refractoriness' in noninfarcted myocardium of patients with ventricular tachycardia or ventricular fibrillation after myocardial infarction.},
  author={Anand R. Ramdat Misier and Tobias Opthof and Norbert M van Hemel and Jeroen T. Vermeulen and Jacques M. T. de Bakker and Jo J A M T Defauw and F. J. L. Van Capelle and Michiel J. Janse},
  journal={Circulation},
  year={1995},
  volume={91 10},
  pages={2566-72}
}
BACKGROUND Postinfarction ventricular tachycardias (VTs) may degenerate into ventricular fibrillation (VF), but this does not happen in all patients. The underlying mechanism is not exactly known, but dispersion of refractory periods is considered a major factor in both induction and persistence of reentrant arrhythmias in general. Hypertrophied, noninfarcted myocardium has altered electrophysiological characteristics. We hypothesized that noninfarcted ventricular tissue may provide the… CONTINUE READING