Dispersion and insertion polymorphism in two small subfamilies of recently amplified human Alu repeats.

@article{Batzer1995DispersionAI,
  title={Dispersion and insertion polymorphism in two small subfamilies of recently amplified human Alu repeats.},
  author={Mark A Batzer and Carol M. Rubin and Utha Hellmann-Blumberg and Michelle Alegria-Hartman and Esther P. Leeflang and J. David Stern and Hernan A. Bazan and Tamim H. Shaikh and Prescott L Deininger and Carl W. Schmid},
  journal={Journal of molecular biology},
  year={1995},
  volume={247 3},
  pages={
          418-27
        }
}
Newly isolated members of two recently propagated (young) Alu subfamilies were examined for sequence diversity and insertion polymorphism in primate genomes. The smaller subfamily (termed HS-2) is comprised of approximately 5 to 25 members, while the larger (termed Sb2) includes approximately 125 to 600 members. Individual members of these Alu subfamilies share distinguishing sets of diagnostic mutations, are well-conserved relative to each other, and have expanded in the human lineage. At… CONTINUE READING

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