Dispersal state of multiwalled carbon nanotubes elicits profibrogenic cellular responses that correlate with fibrogenesis biomarkers and fibrosis in the murine lung.

@article{Wang2011DispersalSO,
  title={Dispersal state of multiwalled carbon nanotubes elicits profibrogenic cellular responses that correlate with fibrogenesis biomarkers and fibrosis in the murine lung.},
  author={Xiuli Wang and Tian Xia and Susana Addo Ntim and Zhaoxia Ji and Sijie Lin and Huan Meng and Choong-Heui Chung and Saji George and Haiyuan Zhang and Meiying Wang and Ning Li and Yang Yang and Vincent Castranova and Somenath Mitra and James C. Bonner and Andr{\'e} E Nel},
  journal={ACS nano},
  year={2011},
  volume={5 12},
  pages={9772-87}
}
We developed a dispersal method for multiwalled carbon nanotubes (MWCNTs) that allows quantitative assessment of dispersion on profibrogenic responses in tissue culture cells and in mouse lung. We demonstrate that the dispersal of as-prepared (AP), purified (PD), and carboxylated (COOH) MWCNTs by bovine serum albumin (BSA) and dipalmitoylphosphatidylcholine (DPPC) influences TGF-β1, PDGF-AA, and IL-1β production in vitro and in vivo. These biomarkers were chosen based on their synergy in… CONTINUE READING
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Comparative Pulmonary A RTIC

  • D. B. Warheit, B. R. Laurence, K. L. Reed, D. H. Roach, G.A.M. Reynolds, T. R. Webb
  • LE WANG ET AL. VOL
  • 2011

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