Disparity in the DNA translocase domains of SWI/SNF and ISW2

Abstract

An ATP-dependent DNA translocase domain consisting of seven conserved motifs is a general feature of all ATP-dependent chromatin remodelers. While motifs on the ATPase domains of the yeast SWI/SNF and ISWI families of remodelers are highly conserved, the ATPase domains of these complexes appear not to be functionally interchangeable. We found one reason… (More)
DOI: 10.1093/nar/gks007

5 Figures and Tables

Topics

  • Presentations referencing similar topics