Disparate distribution of activating and inhibitory killer cell immunoglobulin-like receptor genes in patients with systemic lupus erythematosus.

@article{Hou2010DisparateDO,
  title={Disparate distribution of activating and inhibitory killer cell immunoglobulin-like receptor genes in patients with systemic lupus erythematosus.},
  author={Y Hou and Y Zhang and Y-L Jiao and L Wang and J-f Li and Z-L Pan and Q Yang and H Sun and Y Zhao},
  journal={Lupus},
  year={2010},
  volume={19 1},
  pages={20-6}
}
The genes of killer cell immunoglobulin-like receptors (KIRs), which are involved in the activation of T cells and natural killer cells, are highly variable. In recent years, the role of KIRs in autoimmune diseases has received increasing attention. The present study was undertaken to determine the association of the polymorphism of KIR genes with the susceptibility to systemic lupus erythematosus (SLE). The polymorphism of KIR genes of 93 patients with SLE together with 123 healthy donors as… CONTINUE READING