Disorders of interstitial cells of Cajal.

  title={Disorders of interstitial cells of Cajal.},
  author={Alan J Burns},
  journal={Journal of pediatric gastroenterology and nutrition},
  volume={45 Suppl 2},
Interstitial cells of Cajal (ICCs) have, in the past 2 decades, been recognised as important elements in the regulation of gastrointestinal motility. Specifically, they have been shown to be critical for the generation and propagation of electrical slow waves that regulate the phasic contractile activity of gastrointestinal smooth muscle, and for mediating neurotransmission from enteric motor neurons to smooth muscle cells. These different functional roles are carried out by different… CONTINUE READING