Disentangling the complexity of the skin dendritic cell network.

  title={Disentangling the complexity of the skin dendritic cell network.},
  author={Sandrine Henri and Martin Guilliams and Lionel Franz Poulin and Samira Tamoutounour and Laurence Ardouin and Marc Dalod and Bernard Malissen},
  journal={Immunology and cell biology},
  volume={88 4},
Using 'knockin' mice to track and ablate dendritic cells (DCs) expressing notably the langerin (Cd207) gene, it has been possible to identify five DC subsets within the skin and to assess whether functional specialization exists among them. The present review summarizes recent information concerning the phenotype and the function of these five DC subsets… CONTINUE READING