Disease-specific eQTL screening reveals an anti-fibrotic effect of AGXT2 in non-alcoholic fatty liver disease.

@article{Yoo2021DiseasespecificES,
  title={Disease-specific eQTL screening reveals an anti-fibrotic effect of AGXT2 in non-alcoholic fatty liver disease.},
  author={Taekyeong Yoo and Sae Kyung Joo and Hyo Jung Kim and Hyun Young Kim and Hyungtai Sim and Jieun Lee and Hee-Hoon Kim and Sunhee Jung and Youngha Lee and Oveis Jamialahmadi and Stefano Romeo and Won-Il Jeong and Geum-Sook Hwang and Keon Wook Kang and Jae Woo Kim and Won Kim and Murim Choi},
  journal={Journal of hepatology},
  year={2021}
}
Deciphering the genetic links between NAFLD and co-occurring conditions using a liver gene regulatory network
TLDR
It is demonstrated that MBOAT7 and IL32, which are associated with NAFLD progression, are regulated by spatially constrained eQTLs that are enriched for an association with liver enzyme levels.
The Chromatin Accessibility Landscape of Nonalcoholic Fatty Liver Disease Progression
TLDR
This study presents a genome-wide chromatin accessibility profile of 44 liver samples spanning the full histological spectrum of nonalcoholic fatty liver disease (NAFLD) and reveals the gene-regulatory interactions and noncoding factors that can affect NAFLD progression.