Disease progression or pseudoprogression after concomitant radiochemotherapy treatment: pitfalls in neurooncology.

@article{Brandes2008DiseasePO,
  title={Disease progression or pseudoprogression after concomitant radiochemotherapy treatment: pitfalls in neurooncology.},
  author={Alba A Brandes and Alicia Tosoni and Federica Spagnolli and Giampiero Frezza and Mariacristina Leonardi and Fabio Calbucci and Enrico Franceschi},
  journal={Neuro-oncology},
  year={2008},
  volume={10 3},
  pages={
          361-7
        }
}
Although radionecrosis has been exhaustively described in depth in the neurooncological literature, its diagnosis is still a challenging issue because its radiological pattern is frequently indistinguishable from that of tumor recurrence. This review discusses the causes of radionecrosis and the potential effect of adjuvant chemotherapy concomitant with radiotherapy on its rate and onset. The potential pitfalls in clinical studies attempting to make a differential diagnosis between… CONTINUE READING

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