Disease-oriented Genome Networks Diseases of the Nervous System Network: Systematic Gene Identification and Functional Analyses in Common CNS Disorders Project: Identification of Genetic Risk Factors of Parkinsons Disease

Abstract

Introduction Parkinson disease is a clinically defined syndrome, characterized by variable combinations of akinesia, rigidity, tremor and postural instability. These symptoms are caused by a degeneration of dopaminergic neurons of the substantia nigra, leading to a deficiency of dopamine in their striatal projection areas. Characteristic eosinophilic… (More)

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@inproceedings{Gasser2005DiseaseorientedGN, title={Disease-oriented Genome Networks Diseases of the Nervous System Network: Systematic Gene Identification and Functional Analyses in Common CNS Disorders Project: Identification of Genetic Risk Factors of Parkinsons Disease}, author={Thomas Gasser}, year={2005} }