Disease not genetic but infectious: multiple tuberculomas and fibrinous pericarditis as symptoms pathognomonic for tuberculosis of Frederic Chopin

@article{Witt2018DiseaseNG,
  title={Disease not genetic but infectious: multiple tuberculomas and fibrinous pericarditis as symptoms pathognomonic for tuberculosis of Frederic Chopin},
  author={Michał Witt and Artur Szklener and Wojciech M. Marchwica and Tadeusz Dobosz},
  journal={Journal of Applied Genetics},
  year={2018},
  volume={59},
  pages={471-473}
}
Chopin’s heart, generally enlarged, presented morphologic features pathognomonic for fibrinous pericarditis presumably of tubercular origin: multiple nodular hyalinization foci—tuberculomas and fibrillary coating covering the whole surface of pericardium (“frosted heart”). We show that these features differ significantly from post mortem-formed inorganic crystalline deposits, mold colonies, or fat deposits known from various preserved anatomical objects stored for a long period of time. In our… 
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Background Citations
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4 Citations

Inheritance vs. infectivity as a mechanism of malady and death of Frederic Chopin
TLDR
It can be stated with high probability that the composer suffered from a long lasting tuberculosis as a primary disease, which was the cause of progressive deterioration of his physical condition and numerous symptoms mainly from the respiratory tract.
CASE OF FREDERIC CHOPIN: COULD MUSIC BE A SYMPTOM?
TLDR
Analysis shows that Chopin's creative process did not depend on the circumstances of his personal life, nor on his health, and analysis of his music as a component of professional anamnesis does not provide additional information for diagnosis.
"…In the immortal forms of beauty": Frédéric Chopin seen through the eyes of the father of Brazilian neurological semiology.
TLDR
Aloysio de Castro reinforced the bonds of music and Medicine and provided lessons on Musicology that may very well be as suited to a hospital as they are to a concert hall.
Ten Famous Composers of the Romantic Era and Their Causes of Death
The musical composers in the Romantic Era (1800–1910) strived for compositions that expressed human life, including happiness, harmony, and despair. They lived in a period in which freedom of…

References

SHOWING 1-7 OF 7 REFERENCES
Tuberculous Pericarditis
TLDR
Research is needed to improve the diagnosis, assess the effectiveness of adjunctive steroids, and determine the impact of HIV infection on the outcome of tuberculous pericarditis.
Cystic fibrosis--a probable cause of Frédéric Chopin's suffering and death.
TLDR
This work presents F. Chopin's case history and discusses cons and pros for cystic fibrosis as the cause of F. chopin's suffering and death.
[Tuberculous pericarditis].
  • Soloff
  • Medicine
    Arquivos brasileiros de medicina
  • 1953
Composers and tuberculosis: the effects on creativity.
  • E. Abbott
  • Medicine
    Canadian Medical Association journal
  • 1982
TLDR
Tuberculosis infection was endemic in Northern Europe but in Spain and Italy the disease was less frequent and Crowding and poor sanitation and hygiene led to spread of the disease and by the 18th century, the death rate reached its peak.
Tuberculoma of the myocardium in a patient with tuberculous meningitis treated with streptomycin.
A Closer Look at Frederic Chopin's Cause of Death.
Frédéric Chopin’s telltale heart
  • Medicine
    Nature
  • 2017