Disease-modifying anti-rheumatic drug use in pregnant women with rheumatic diseases: a systematic review of the risk of congenital malformations.

@article{Baldwin2016DiseasemodifyingAD,
  title={Disease-modifying anti-rheumatic drug use in pregnant women with rheumatic diseases: a systematic review of the risk of congenital malformations.},
  author={Corisande Baldwin and Antonio Avina-Zubieta and Sharan K. Rai and Erin C. Carruthers and Mary A De Vera},
  journal={Clinical and experimental rheumatology},
  year={2016},
  volume={34 2},
  pages={172-83}
}
OBJECTIVES Despite the high incidence of rheumatic diseases during the reproductive years, little is known about the impact of disease-modifying anti-rheumatic drug (DMARD) use during pregnancy. Our objective was to systematically review and appraise evidence in women with rheumatic disease on the use of traditional and biologic DMARDs during pregnancy and the risk of congenital malformation outcomes. METHODS We conducted a systematic search of MEDLINE, EMBASE, and INTERNATIONAL… CONTINUE READING

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