Disease modification of breast cancer-induced bone remodeling by cannabinoid 2 receptor agonists.

@article{LozanoOndoua2013DiseaseMO,
  title={Disease modification of breast cancer-induced bone remodeling by cannabinoid 2 receptor agonists.},
  author={Alysia N Lozano-Ondoua and Katherine E Hanlon and Ashley M Symons-Liguori and Tally Marie Largent-Milnes and Josh J Havelin and Henry L Ferland and Anupama Chandramouli and Mabel Owusu-Ankomah and Tijana Nikolich-Zugich and Aaron P Bloom and Juan Miguel Jim{\'e}nez-Andrade and Tamara E King and F rank Porreca and Mark A. Nelson and Patrick W Mantyh and Todd W. Vanderah},
  journal={Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research},
  year={2013},
  volume={28 1},
  pages={92-107}
}
Most commonly originating from breast malignancies, metastatic bone cancer causes bone destruction and severe pain. Although novel chemotherapeutic agents have increased life expectancy, patients are experiencing higher incidences of fracture, pain, and drug-induced side effects; furthermore, recent findings suggest that patients are severely undertreated… CONTINUE READING